August 11, 2016 -Article in Clinical Lab Products (CLP) magazine by Cynvenio Chief Science Officer, Paul Dempsey, PhD, discussing improvements in liquid biopsy techniques and the analysis of rare cancer-derived events present among normal cells or DNA.
April 5, 2016 — Molecular diagnostic approaches to cancer detection and monitoring can benefit from a multiple-template strategy that analyzes DNA from circulating tumor cells (ctcDNA) and circulating cell free DNA (ccfDNA) in blood, as well as from tissue biopsies, according to new NCI-supported clinical trial published by scientists from Cynvenio Biosystems, Inc., and collaborators. The new research was published online in the journal Oncotarget.
April 1, 2016 - Genome web article highlighting a trial by researchers at Mount Sinai to evaluate the genomic profiles of ctDNA and CTCs as well as phenotypic features of CTCs in patients with triple negative breast cancer to study the relationships between the two and how they correlate with disease. The group will use Cynvenio's LiquidBiopsy microfluidic system to isolate CTCs, ctDNA, and germline DNA.
March 3, 2016 –Cynvenio Biosystems, Inc. honors Triple Negative Breast Cancer Day by launching a clinical trial for women with triple negative breast cancer (TNBC) using the company’s non-invasive liquid biopsy technology to monitor participants and identify early signs of metastasis.
February 10, 2016 – Cynvenio announces the availability of the Concordia™ cell-free DNA (cfDNA) purification sample preparation upgrade for its multi-template analysis LiquidBiopsy® platform. When coupled with Thermo Fisher Scientific’s Ion Torrent™ next-generation sequencing (NGS) systems, Cynvenio’s workflow provides a comprehensive molecular characterization of tumor cell DNA for cancer research samples from a standard blood draw.
December 28, 2015 – Cynvenio Biosystems, Inc. and ATGen Global, a Korea-based biotech company, announced the launch of a pilot study to evaluate a new method for early detection of cancer in women who have completed treatment for triple-negative breast cancer (TNBC) and show no radiographic signs of metastases.
December 2, 2015 – Cynvenio announces that it has entered into a strategic collaboration with the Institute of Regional Health Research for the Region of Southern Denmark at the University of Southern Denmark to conduct a wide array of clinical cancer trials using Cynvenio’s Triple Play LiquidBiopsy® platform.
October 1, 2015 – Cynvenio Biosystems, Inc. announces that it has developed, validated, and fully implemented a PD-L1 (Programmed Death-Ligand 1) assay for circulating tumor cells (CTCs) obtained via its LiquidBiopsy® technology for several tumor subtypes.
September 29, 2015 – Cynvenio Biosystems, Inc. and ATGen Global, a private biotech company in Korea that manufactures and supplies a wide array of recombinant proteins and antibodies worldwide, announces the companies a collaborative partnership to bring ATGen’s NK Vue™ test to the US market.
September 8, 2015 –Cynvenio Biosystems, Inc. announces that the Accreditation Committee of the College of American Pathologists (CAP) has awarded accreditation to its laboratory. Cynvenio has been certified by CLIA, the U.S. Clinical Laboratory Improvement Amendments, since 2013.